Some of the major pharmacies including Quinn, Helios, Washington Homeopathic, and Boiron all make their remedies on a Korasakoff machine which makes very accurate dilutions with succussion. Mike Quinn designed his version of the machine and John Morgan at Helios made his and sold one to Washington Homeopathic.
But the most popular Korsakoff machine is Labotics' K-TRONIC used by Boiron (1 machine), Dolisos (11), Heel (3), IMO (1), Hering (1), UNDA (5), CEMON (1), Korres (2), Homeocan-Homeoplab (1), Arkopharma (1), Debrus-Tensi (3), SBL (1), Hom. Hospital & Stores (1), and others. More than 80 K-TRONIC machines operate day and night throughout the world, and 99% of Europe's K potencies are made with Labotics' machines.
They also have less expensive and more purchased modules. IMPREGMAT has sold over 250 modules and their DYNAMAT over 400.
Julian Winston has a discussion of manufacturing and potencies from the 1925 B & T catalogue on his web site talking about Hahnemannian methods
Korsakoff discovered grafting. F.E. Boericke at the turn of the century, said that grafting is filled with possible problems of contamination.
Julian Winston has a definite opinion on the subject: Grafting? sure you CAN do it. But why? The ONLY reason to graft a remedy is when the original is NOT AVAILABLE at all. I can't see grafting a 30th of Ignatia, when we have supplies for new stuff so readily at hand. A. J. Tafle wrote a piece on grafting which said that a lot of failures in prescribing were seen not because it was the wrong remedy, but because it was a graft. And when a fresh remedy was used, it acted. And grafting does not support the pharmacies, and IMO, without THEM we'd have nothing.
Wait until the bottle has little left in it. Then add blank granules and succuss. The size of the pellet doesn't matter nor does the composition of the material matter either. A pure sugar pellet is softer.
The same, but with alcohol. One method is to place one or two pellets of a potency on top of a vial of blank pellets, add a few drops of alcohol solution at least 97% enough to cover all of the pellets and then succuss the vial.