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The classical "split dose" is prepared by dissolving one dose of dry remedy (i.e. one pellet) in a glass of water and then giving a teaspoon from that solution as a dose. The remainder is discarded. Giving a split dose is firmly anchored in classical homeopathy. In the search for the minimal dose, Hahnemann explored smaller and smaller remedy doses. As a consequence, he wanted to divide even a single pellet into smaller doses, and dissolving it in water achieves just that. It turned out that in doing so, the remedy acts much deeper and gentler than when given dry on the tongue in one whole dose. This mode of administering a remedy was introduced in the 5th edition of the Organon and has been even expanded in the 6th edition. According to the 6th editon, all remedies prepared as LM potencies (the only one Hahnemann advocates in his last edition) are to be given as a "split dose."
The other way to interpret the term "split dose" is the practice of giving, say, 2 pellets in the evening and 2 the next morning, instead of all 4 at once. The rationale behind that being the cyclical nature of the body's sensitivity to remedies. By spacing them 12 hours or so apart, you are more likely the body when the remedy works the best. This is not the classical "split dose."
